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    News

    Medical Students Explore Neurodegeneration at the SyNergy Science Day

    6 Feb 2026 | Event Recap

    Organized by the SyNergy Translational Teaching Track, the SyNergy Science Day welcomed around 300 medical students for a hands-on and inspiring exploration of neurodegenerative disease research. In…

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    Advanced Clinician Scientist Program for Comprehensive Neuroscience (PROMISE)

    3 Feb 2026

    The BMFTR-funded program PROMISE is a structured qualification program for Advanced Clinician Scientists that fosters long-term and sustainable career trajectories. It supports physicians who,…

    New course on Alzheimer's disease (in German)

    12 Jan 2026

    For those affected, their families, and interested laypersons. "Alzheimer's disease – causes, progression, and current research". In collaboration with the SyNergy Cluster.

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    Research Spotlight

    TREM2 Levels Shape Microglial Metabolic Fitness

    6 Feb 2026 | Research Spotlight

    This study shows that microglial TREM2 is not an on/off signal but a graded axis that tracks with microglial state and function. Using a new Trem2-mKate2 reporter mouse, the authors link higher TREM2…

    Podcast

    57 Clusters of Excellence, 1 podcast. This episode of “Exzellent erklärt - Spitzenforschung für alle” focuses on our research with Thomas Misgeld and Anna-Sophia Wahl. Topics include research into common neurological diseases such as Alzheimer's, multiple sclerosis and stroke, the self-healing powers of the brain and the Cluster's interdisciplinary approach. Current advances in repair mechanisms, the importance of neuronal plasticity and the use of modern technologies such as AI for research are discussed.

      podcast cover exzellent erklärt #54
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    SyNergy is:

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    27
    Tandem projects
    3288
    Publications

    The Cluster of Excellence SyNergy (Munich Cluster for Systems Neurology) investigates how complex neurological diseases such as Alzheimer's and Parkinson's Disease, stroke, or multiple sclerosis develop. Even though these diseases differ significantly in their clinical manifestations, overlapping mechanisms are involved in their development. Using systems neurology as a new interdisciplinary approach, researchers can better map the processes involved in neurovascular, neurodegenerative, and neuroimmunological diseases and develop approaches for novel therapies. The cluster has been funded by the German Research Foundation (DFG) since 2012.

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    Participating Universities
     LMU logo in white
     TUM logo in white
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    Helmholtz Munich logo in white 
     Logo Max Planck Gesellschaft 

    SyNergy is funded by the Deutsche Forschungsgemeinschaft (German Research Foundation) within the framework of the German Excellence Strategy (EXC 2145 SyNergy – ID 390857198). The Excellence Strategy promotes outstanding research at German universities. 

    Contact

    Munich Cluster for Systems Neurology (SyNergy)

    Feodor-Lynen-Str. 17
    81377 Munich
    +49 (0)89 4400-46497
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