CNS Treg cells have alternative functions but run on conventional fuel.
Nat Immunol. 2022 Jun;23(6):818-819. doi: 10.1038/s41590-022-01201-6. PMID: 35618830.
Authors/Editors: | Korn T. |
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Publication Date: | 2022 |
Abstract
Ectopic expression of IL-2 in the central nervous system (CNS) is sufficient to create an organ-restricted niche for tissue-resident regulatory T cells that support re-establishment of homeostasis after multiple types of tissue injury in the CNS.