A new way of D/Ealing with protein misfolding.
Mol Cell. 2021 Oct 21;81(20):4114-4115. doi: 10.1016/j.molcel.2021.09.025. PMID: 34686313.
|Authors/Editors:||Sitron CS, Hartl FU.|
Huang et al. (2021) show that proteins containing aspartate- and glutamate-rich stretches represent a putative new class of ATP-independent molecular chaperones that operate on diverse client proteins in vitro and protect bona fide interactors against aggregation in cells.