Mitochondrial Ejection for Cardiac Protection: The Macrophage Connection.
Cell Metab. 2020 Oct 6;32(4):512-513. doi: 10.1016/j.cmet.2020.09.014. PMID: 33027673.
| Authors/Editors: | Bartelt A, Weber C. |
|---|---|
| Publication Date: | 2020 |
Abstract
Mitochondrial dysfunction is a hallmark of heart disease. Nicolás-Ávila et al. (2020) now find that cardiomyocytes eject dysfunctional mitochondria in exopher vesicles, which require elimination by specialized heart-resident macrophages, altogether supporting proper heart function.
