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Dementia risk after transient ischaemic attack and stroke.

Lancet Neurol. 2019 Mar;18(3):223-225. doi: 10.1016/S1474-4422(18)30497-6. Epub 2019 Feb 12.

Authors/Editors: Dichgans M.
Publication Date: 2019


About 20% of patients who are admitted to hospital for stroke develop dementia within the first year after the event; incidence is higher in those with recurrent stroke and lower in those with first-ever stroke.
Furthermore, roughly one in ten patients with first-ever stroke already has dementia at event onset.
As survival rates after stroke increase, dementia has become a growing concern for patients, families, and health-care providers. Previous studies have identified predictors of post-stroke dementia, including age, low educational attainment, previous stroke, stroke severity, dysphasia, diabetes, atrial fibrillation, and leucoaraiosis on brain imaging. However, this information mostly originates from hospital-based studies, which are prone to selection bias and other biases, including attrition. There are few data for dementia risk after transient ischemic attack or minor stroke, which together account for about 70% of cerebrovascular events. Also, information is scarce about the extent to which the incidence of dementia after transient ischaemic attack or stroke is higher than age-specific dementia incidence in the general population.

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