Munich Cluster for Systems Neurology

Breadcrumb Navigation


Catching filopodia: Exosomes surf on fast highways to enter cells

J Cell Biol. 2016 Apr 25;213(2):143-5. doi: 10.1083/jcb.201604024. Epub 2016 Apr 25.

Authors/Editors: Schneider A, Simons M.
Publication Date: 2016


The mechanisms of exosomal uptake and their intracellular itinerary are not understood. In this issue, Heusermann et al. (2016. J Cell. Biol. show that exosomes surf filopodia and are endocytosed in a process reminiscent to virus entry. Intraendosomal exosomes travel to the ER and are distributed to lysosomal compartments.

Related Links