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Nick Your DNA, Mark Your Chromatin.

Mol Cell. 2016 Oct 6;64(1):7-9. doi: 10.1016/j.molcel.2016.09.023.

Authors/Editors: Nardozza AP, Ladurner AG.
Publication Date: 2016

2016_11_nardozza

Abstract

DNA damage induces chemical and structural changes in our chromatin-embedded genome. In a recent issue of Nature Communications, Grundy et al. (2016) identify a role for PARP3 in the repair of single-strand breaks and reveal that PARP3 mono-ADP-ribosylates nucleosomal histone H2B.

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