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ACF Takes the Driver's Seat

Mol Cell. 2014 Aug 7;55(3):345-6. doi: 10.1016/j.molcel.2014.07.014.

Authors/Editors: Singh HR, Ladurner AG.
Publication Date: 2014


ISWI family chromatin remodeling enzymes generate regularly spaced nucleosome arrays. In a recent Nature report, Hwang et al. (2014) describe how ACF gauges the length of linker DNA when deciding to accelerate nucleosome sliding or to put on the brakes.