Ion channels boost axonal injury in multiple sclerosis
Nat Med. 18(12):1743-5 (2012)
Authors/Editors: | Hohlfeld R. |
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Publication Date: | 2012 |
Abstract
In neuroinflammatory diseases such as multiple sclerosis, ion channels may fan the embers of neurodegeneration.
A new study shows that the cation channel TRPM4 (transient receptor potential melastatin 4) crucially contributes to axonal loss in an animal model of multiple sclerosis.