Ion channels boost axonal injury in multiple sclerosis
Nat Med. 18(12):1743-5 (2012)
In neuroinflammatory diseases such as multiple sclerosis, ion channels may fan the embers of neurodegeneration.
A new study shows that the cation channel TRPM4 (transient receptor potential melastatin 4) crucially contributes to axonal loss in an animal model of multiple sclerosis.