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Press Release: Flow of cerebrospinal fluid regulates neural stem cell division

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper published in the journal ‘Cell Stem Cell’, scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München (LMU) including SyNergy members Magdalena Götz and Benedikt Grothe have shown how this works. They found that ion channels play a key role in mediating force signals to the neural stem cells to activate them.

18.05.2018

The ancient Greek aphorism panta rhei means “everything flows”, a phrase used by philosophers to describe the constant flux and interplay between the past and renewal. A recent paper lends this relationship a whole new meaning: a team of researchers including the SyNergy Members Prof. Magdalena Götz and Prof. Benedikt Grothe has discovered that the flow of cerebrospinal fluid is a key signal for neural stem cell renewal.

Press release Helmholtz Zentrum München

Die altgriechische Formel „Panta rhei“ bedeutet so viel wie „alles fließt“. Damit beschrieben die Philosophen den steten Wandel und das Wechselspiel von Vergänglichkeit und Erneuerung. Eine aktuelle Arbeit verleiht diesem Zusammenhang ganz neue Bedeutung: Die Forschenden um SyNergy Mitglieder Prof. Magdalena Götz und Prof. Benedikt Grothe fanden heraus, dass der Fluss der Gehirnflüssigkeit zur Erneuerung von Stammzellen führen kann.

Pressemeldung Helmholtz Zentrum München