Munich Cluster for Systems Neurology

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  • 26.01.2021

    Nature Communications Editors’ Highlights of recent study by SyNergy members

    The editors at Nature Communications have put together an Editors’ Highlights webpage of recent research called “From brain to behaviour”. The article entitled “Myelin replacement triggered by single-cell demyelination in mouse” by SyNergy members Martina Schifferer, Martin Kerschensteiner, and Thomas Misgeld was featured. more

  • 26.01.2021

    Press Release: Immune cells attack synapses

    Inflammation causes cerebral cortex dysfunction in multiple sclerosis. Damage to the brain gray matter plays an important role in the progression of multiple sclerosis. A team of neuroscientists including SyNergy members Thomas Misgeld, Martin Kerschensteiner, and Ruben Portugues has now shown that the cause are inflammatory responses that lead to synapse loss, reducing neuronal activity. Targeted inhibition of these immune cells could mitigate such synaptic damage, and therefore provides a promising therapeutic option for progressive multiple sclerosis. more

  • 28.12.2020

    Press Release: Quick look under the skin

    Self-learning algorithms analyze medical imaging data. Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience. Artificial neural networks open up new possibilities, as shown in a new publication with SyNergy member Ali Ertürk. They require just seconds to interpret whole-body scans of mice and to segment and depict the organs in colors, instead of in various shades of gray. This facilitates the analysis considerably. more

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