Munich Cluster for Systems Neurology

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Curriculum vitae Prof. Dr. Thomas Misgeld


    • 1991-1998 Medical studies (TU Munich)
    • 1998 Medical degree
    • 1994-99 M.D. thesis, Max-Planck-Institute of Neurobiology & TU Munich
    • 1999-2000 Internship (AiP), Institute for Clinical Neuroimmunology
    • 2000 Medical license (‘Approbation’)
    • 2000-2004 Post-doc, Department of Anatomy & Neurobiology, Washington University, St. Louis
    • 2004-2006 Post-doc, Department of Molecular & Cellular Biology, Harvard University, Cambridge

Academic positions & appointments

    • 2006-2011 Sofja-Kovalevskaja young investigator group leader, TUM
    • 2006 - 2016 Summer faculty, Neurobiology, Marine Biological Laboratory, Woods Hole, USA
    • 2009 - 2011 W3 Professor, Chair for Biomolecular Sensors, TUM (tenure track)
    • since 2011 W3 Professor and DirectorInstitute of Neuronal Cell Biology, TUM

Collaborative research

    • 2008 - 2012 Project leader, DFG-SFB596
    • 2006 - 2015 Project leader, DFG-IRTG1373
    • 2009 - 2012 Project leader, ERA-Net “iPSoALS”
    • 2010 - 2013 Project leader, ERA-Net “2-photon imaging”
    • since 2013 Project leader, DFG-SFB870
    • since 2012 Co-Speaker, Munich Cluster of Systems Neurology (SyNergy)
    • since 2017 Co-Speaker, MSc ‘Biomedcial Neuroscience’ as part of EliteNetwork Bavaria

Awards & honors

    • 1993 - 1998 Fellow of the German Academic National Foundation (Studienstiftung d. Dt. Volkes).
    • 1998 Thesis award for the best thesis in medicine, TU München
    • 2002 Emmy-Noether (phase I) fellowship, DFG
    • 2004 Wyeth MS Young Investigator Award, German Neurological Society
    • 2005 Robert-Feulgen Award, Histopathological Society
    • 2005 Offer of Emmy-Noether (phase II) grant, DFG
    • 2005 Offer Canadian Research Chair, tier II
    • 2006 Sofja-Kovalevskaja Award, Alexander-von-Humboldt Foundation
    • 2007 Schilling Award, German Neuroscience Foundation
    • 2008 Hans-Fischer Fellowship, TUM Institute for Advanced Study
    • 2012 Alzheimer’s Research Prize, Breuer Foundation
    • 2014 ERC Consolidator Grant

10 key papers

    • Misgeld T, Schwarz T. Mitostasis in neurons: Maintaining mitochondria in an extended cellular
      architecture. Neuron 96:651-66 (2017)
    • Brill MS, Kleele T, Ruschkies L, Wang M, Marahori NA, Reuter M, Hausrat TJ, Weigand E, Fisher M, Ahles A, Engelhardt S, Bishop DL, Kneussel M, Misgeld T. Branch-specific microtubule destabilization mediates axon branch loss during neuromuscular synapse elimination. Neuron 92:845-56 (2016)
    • Breckwoldt MO, Pfister F, Bradley PM, Marinković P, Williams PW, Brill MS, Plomer B, Schmalz A, St Clair DK, Naumann R, Griesbeck O, Schwarzländer M, Godinho L, Bareyre FM, Dick TP, Kerschensteiner M*, Misgeld T*. Multi-parametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo. Nat Med 20: 555-60 (2014) (* equal senior authorship)
    • Sorbara CD, Wagner NE, Ladwig A, Nikic I, Merkler D, Kleele T, Marinković P, Godinho L, Bareyre FM, Bishop D, Misgeld T*, Kerschensteiner M.* Pervasive axonal transport deficits in multiple sclerosis models. Neuron 84:1183-90 (2014) (* equal senior authorship)
    • Williams PR, Marincu BN, Sorbara CD, Mahler CF, Schumacher A-M, Griesbeck O, Kerschensteiner M*, Misgeld T*. A recoverable state of axon injury persists for hours after spinal cord contusion in vivo. Nat Commun 5: 5683 (2014) (* equal senior authorship)
    • Bishop D, Nikić I, Brinkoetter M, Knecht S, Potz S, Kerschensteiner M* & Misgeld T.* Near-infrared branding efficiently correlates light and electron microscopy. Nat Methods 5:568-70 (2011) (* equal senior authorship)
    • Nikić I, Merkler D, Sorbara C, Brinkoetter M, Kreutzfeld M, Bareyre FM, Brück W, Bishop D, Misgeld T* & Kerschensteiner M*. A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis. Nat Med 17:495-9 (2011) (* equal senior authorship)
    • Misgeld T*, Kerschensteiner M*, Bareyre FM, Burgess RW & Lichtman JW. In vivo imaging axonal transport of mitochondria in mammals. Nat Methods 4:559-61 (2007) (* equal contribution)
    • Misgeld T & Kerschensteiner M. In vivo imaging of the diseased nervous system. Nat Rev Neurosci 7:449-63 (2006)
    • Kerschensteiner M, Schwab M, Lichtman JW & Misgeld T. In vivo imaging of axonal degeneration and regeneration in the injured spinal cord. Nat Med 11:572-7 (2005)

Responsible for content: Prof. Dr. Thomas Misgeld