Publications Schifferer

2023

• Dawkins E, Derks RJE, Schifferer M, Trambauer J, Winkler E, Simons M, Paquet D, Giera M, Kamp F, Steiner H (2023)
  Membrane lipid remodeling modulates γ-secretase processivity.
  J Biol Chem. 2023 Feb 15:103027. doi: 10.1016/j.jbc.2023.103027. Epub ahead of print. PMID: 36805335.
• Djannatian M, Radha S, Weikert U, Safaiyan S, Wrede C, Deichsel C, Kislinger G, Rhomberg A, Ruhwedel T, Campbell DS, van Ham T, Schmid B, Hegermann J, Möbius W, Schifferer M, Simons M (2023)
  Myelination generates aberrant ultrastructure that is resolved by microglia.
  J Cell Biol. 2023 Mar 6;222(3):e202204010. doi: 10.1083/jcb.202204010. Epub 2023 Jan 13. PMID: 36637807; PMCID: PMC9856851.
• Nalbach K, Schifferer M, Bhattacharya D, Ho-Xuan H, Tseng W, Williams LA, Stolz A, Lichtenthaler SF, Elazar Z, Behrends C (2023)
  Spatial proteomics reveals secretory pathway disturbances caused by neuropathy-associated TECPR2.
  Nat Commun. 2023 Feb 16;14(1):870. doi: 10.1038/s41467-023-36553-6. PMID: 36797266; PMCID: PMC9935918.

2022

• Arends M, Weber M, Papan C, Damm M, Surma MA, Spiegel C, Djannatian M, Li S, Connell L, Johannes L, Schifferer M, Klose C, Simons M (2022)
  Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry.
  iScience. 2022 Oct 10;25(11):105323. doi: 10.1016/j.isci.2022.105323. PMID: 36310581; PMCID: PMC9615322.
• Herwerth M, Kenet S, Schifferer M, Winkler A, Weber M, Snaidero N, Wang M, Lohrberg M, Bennett JL, Stadelmann C, Hemmer B, Misgeld T (2022)
  A new form of axonal pathology in a spinal model of neuromyelitis optica.
  Brain. 2022 Feb 24:awac079. doi: 10.1093/brain/awac079. Epub ahead of print. PMID: 35202467.
• Kaya T, Mattugini N, Liu L, Ji H, Cantuti-Castelvetri L, Wu J, Schifferer M, Groh J, Martini R, Besson-Girard S, Kaji S, Liesz A, Gokce O, Simons M (2022)
  CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging.
  Nat Neurosci. 2022 Nov;25(11):1446-1457. doi: 10.1038/s41593-022-01183-6. Epub 2022 Oct 24. PMID: 36280798; PMCID: PMC9630119.
• Liesche-Starnecker F, Schifferer M, , Schlegel J, Vollmuth Y, Rubbenstroth D, Delbridge C, Gempt J, Lorenzl S, Schnurbus L, Misgeld T, , Rosati M, Beer M, Matiasek K, Wunderlich S, Finck T (2022)
  Hemorrhagic lesion with detection of infected endothelial cells in human bornavirus encephalitis
  Acta Neuropathol. 2022 Jun 3:1–3. doi: 10.1007/s00401-022-02442-3. Epub ahead of print. PMID: 35657496; PMCID: PMC9164175.
• Zhou D, Borsa M, Puleston DJ, Zellner S, Capera J, Sanderson S, Schifferer M, Hester SS, Ge X, Fischer R, Jostins L, Behrends C*, Alsaleh G*, Simon AK* (2022)
  Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.
  Nat Commun. 2022 Sep 2;13(1):5174. doi: 10.1038/s41467-022-32718-x. PMID: 36055998; PMCID: PMC9440129..

2021

• Bosch-Queralt M, Cantuti-Castelvetri L, Damkou A, Schifferer M, Schlepckow K, Alexopoulos I, Lütjohann D, Klose C, Vaculčiaková L, Masuda T, Prinz M, Monroe KM, Di Paolo G, Lewcock JW, Haass C, Simons M (2021)
  Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.
  Nat Metab. 2021 Feb;3(2):211-227. doi: 10.1038/s42255-021-00341-7. Epub 2021 Feb 18. PMID: 33619376.
• Colombo A, Dinkel L, Müller SA, Sebastian Monasor L, Schifferer M, Cantuti-Castelvetri L, König J, Vidatic L, Bremova-Ertl T, Lieberman AP, Hecimovic S, Simons M, Lichtenthaler SF, Strupp M, Schneider SA, Tahirovic S (2021)
  Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.
  Nat Commun. 2021 Feb 24;12(1):1158. doi: 10.1038/s41467-021-21428-5. PMID: 33627648.
• Gouna G, Klose C, Bosch-Queralt M, Liu L, Gokce O, Schifferer M, Cantuti-Castelvetri L, Simons M (2021)
  TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination
  J Exp Med. 2021 Oct 4;218(10):e20210227. doi: 10.1084/jem.20210227. Epub 2021 Aug 23. PMID: 34424266.
• Rausch L, Lutz K, Schifferer M, inheim E, Gruber R, Oesterhaus EF, Rinke L, Hellmuth JC, Scherer C, Muenchhoff M, Mandel C, Bergwelt-Baildon M, Simons M, Straub T, Krug AB, Kranich J, Brocker T (2021)
  Binding of phosphatidylserine-positive microparticles by PBMCs classifies disease severity in COVID-19 patients.
  J Extracell Vesicles. 2021 Dec;10(14):e12173. doi: 10.1002/jev2.12173. PMID: 34854246; PMCID: PMC8636722.
• Safaiyan S, Besson-Girard S, Kaya T, Cantuti-Castelvetri L, Liu L, Ji H, Schifferer M, Gouna G, Usifo F, Kannaiyan N, Fitzner D, Xiang X, Rossner MJ, Brendel M, Gokce O, Simons M (2021)
  White matter aging drives microglial diversity.
  Neuron. 2021 Feb 11:S0896-6273(21)00073-8. doi: 10.1016/j.neuron.2021.01.027. Epub ahead of print. PMID: 33606969.
• Schifferer M, Snaidero N, Djannatian M, Kerschensteiner M, Misgeld T (2021)
  Niwaki Instead of Random Forests: Targeted Serial Sectioning Scanning Electron Microscopy With Reimaging Capabilities for Exploring Central Nervous System Cell Biology and Pathology.
  Front Neuroanat. 2021 Oct 13;15:732506. doi: 10.3389/fnana.2021.732506. PMID: 34720890; PMCID: PMC8548362.
• Zellner S, Schifferer M, Behrends C (2021)
  Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
  Mol Cell. 2021 Jan 28:S1097-2765(21)00009-5. doi: 10.1016/j.molcel.2021.01.009. Epub ahead of print. PMID: 33545068.

2020

• Cunha MI, Su M, Cantuti-Castelvetri L, Müller SA, Schifferer M, Djannatian M, Alexopoulos I, van der Meer F, Winkler A, van Ham TJ, Schmid B, Lichtenthaler SF, Stadelmann C, Simons M (2020)
  Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis.
  J Exp Med. 2020 May 4;217(5). pii: e20191390. doi: 10.1084/jem.20191390.
• Kislinger G, Gnägi H, Kerschensteiner M, Simons M, Misgeld T, Schifferer M (2020)
  Multiscale ATUM-FIB Microscopy Enables Targeted Ultrastructural Analysis at Isotropic Resolution.
  iScience. 2020;23(7):101290. doi:10.1016/j.isci.2020.101290 [published online ahead of print, 2020 Jun 20]
• Kranich J, Chlis NK, Rausch L, Latha A, Schifferer M, Kurz T, Foltyn-Arfa Kia A, Simons M, Theis FJ, Brocker T (2020)
  In vivo identification of apoptotic and extracellular vesicle-bound live cells using image-based deep learning.
  J Extracell Vesicles. 2020 Jul 16;9(1):1792683. doi: 10.1080/20013078.2020.1792683. PMID: 32944180; PMCID: PMC7480589.
• Mondo E, Becker SC, Kautzman AG, Schifferer M, Baer CE, Chen J, Huang EJ, Simons M, Schafer DP (2020)
  A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature.
  J Neurosci. 2020;JN-RM-3006-19. doi:10.1523/JNEUROSCI.3006-19.2020 [published online ahead of print, 2020 Jul 13]
• Mukherjee C, Kling T, Russo B, Miebach K, Kess E, Schifferer M, Pedro LD, Weikert U, Fard MK, Kannaiyan N, Rossner M, Aicher ML, Goebbels S, Nave KA, Krämer-Albers EM, Schneider A, Simons M (2020)
  Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain.
  Cell Metab. 2020;S1550-4131(20)30300-4. doi:10.1016/j.cmet.2020.05.01 9[published online ahead of print, 2020 Jun 5]
• Snaidero N, Schifferer M, Mezydlo A, Zalc B, Kerschensteiner M, Misgeld T (2020)
  Myelin replacement triggered by single-cell demyelination in mouse cortex.
  Nat Commun. 2020 Sep 29;11(1):4901. doi: 10.1038/s41467-020-18632-0. PMID: 32994410.

2019

• Djannatian M, Timmler S, Arends M, Luckner M, Weil MT, Alexopoulos I, Snaidero N, Schmid B, Misgeld T, Möbius W, Schifferer M, Peles E, Simons M (2019)
  Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS.
  Nat Commun. 2019 Oct 22;10(1):4794. doi: 10.1038/s41467-019-12789-z.
• Sigmund F, Pettinger S, Kube M, Schneider F, Schifferer M, Schneider S, Efremova MV, Pujol-Martí J, Aichler M, Walch A, Misgeld T, Dietz H, Westmeyer GG (2019)
  Iron-Sequestering Nanocompartments as Multiplexed Electron Microscopy Gene Reporters.
  ACS Nano. 2019 Jun 13. doi: 10.1021/acsnano.9b03140. [Epub ahead of print].