Publications Klein

2019

• Burgold J, Schulz-Trieglaff EK, Voelkl K, Gutiérrez-Ángel S, Bader JM, Hosp F, Mann M, Arzberger T, Klein R, Liebscher S, Dudanova I (2019)
  Cortical circuit alterations precede motor impairments in Huntington's disease mice.
  Sci Rep. 2019 Apr 29;9(1):6634. doi: 10.1038/s41598-019-43024-w.
• Gong J, Gaitanos TN, Luu O, Huang Y, Gaitanos L, Lindner J, Winklbauer R, Klein R (2019)
  Gulp1 controls Eph/ephrin trogocytosis and is important for cell rearrangements during development.
  J Cell Biol. 2019 Aug 13. pii: jcb.201901032. doi: 10.1083/jcb.201901032. [Epub ahead of print]

2017

• Bäuerlein FJB, Saha I, Mishra A, Kalemanov M, Martínez-Sánchez A, Klein R, Dudanova I, Hipp MS, Hartl FU, Baumeister W, Fernández-Busnadiego R (2017)
  In Situ Architecture and Cellular Interactions of PolyQ Inclusions.
  Cell. 2017 Sep 7. pii: S0092-8674(17)30934-0. doi: 10.1016/j.cell.2017.08.009. [Epub ahead of print]
• Del Toro D, Ruff T, Cederfjäll E, Villalba A, Seyit-Bremer G, Borrell V, Klein R (2017)
  Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules
  Cell. 2017 May 4;169(4):621-635.e16. doi: 10.1016/j.cell.2017.04.012.
• Douglass AM, Kucukdereli H, Ponserre M, Markovic M, Gründemann J, Strobel C, Alcala Morales PL, Conzelmann KK, Lüthi A, Klein R (2017)
  Central amygdala circuits modulate food consumption through a positive-valence mechanism.
  Nat Neurosci. 2017 Aug 21. doi: 10.1038/nn.4623. [Epub ahead of print]
• Hosp F, Gutiérrez-Ángel S, Schaefer MH, Cox J, Meissner F, Hipp MS, Hartl FU, Klein R, Dudanova I, Mann M (2017)
  Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function.
  Cell Rep. 2017 Nov 21;21(8):2291-2303. doi: 10.1016/j.celrep.2017.10.097.
• Tai-Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, Ieda M, Takakura N, Nakagawa O, Zhou B, Okabayashi K, Suematsu M, Kitagawa Y, Bastmeyer M, Sato K, Klein R, Navankasattusas S, Li DY, Yamagishi S, Kubota Y (2017)
  Placental labyrinth formation in mice requires endothelial FLRT2-UNC5B signaling
  Development. 2017 Jun 2. pii: dev.149757. doi: 10.1242/dev.149757. [Epub ahead of print]

2016

• Gaitanos TN, Koerner J, Klein R (2016)
  Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion.
  J Cell Biol. 2016 Sep 12;214(6):735-52. doi: 10.1083/jcb.201512010. Epub 2016 Sep 5.
• Gong J Körner R Louise G, Klein R (2016)
  Exosomes mediate cell contact–independent ephrin-Eph signaling during axon guidance
  Journal of Cell Biology. 2016 June 27. DOI: 10.1083/jcb.201601085. pii: jcb.201601085. [Epub ahead of print]
• Jackson VA, Mehmood S, Chavent M, Roversi P, Carrasquero M, Del Toro D, Seyit-Bremer G, Ranaivoson FM, Comoletti D, Sansom MS, Robinson CV, Klein R, Seiradake E (2016)
  Super-complexes of adhesion GPCRs and neural guidance receptors
  Nat Commun. 2016 Apr 19;7:11184. doi: 10.1038/ncomms11184.
• Kania A, Klein R (2016)
  Mechanisms of ephrin-Eph signalling in development, physiology and disease
  Nat Rev Mol Cell Biol. 2016 Jan 21. doi: 10.1038/nrm.2015.16. [Epub ahead of print]

2014

• Gatto G, Morales D, Kania A, Klein R (2014)
  EphA4 Receptor Shedding Regulates Spinal Motor Axon Guidance
  Curr Biol. 2014 Sep 24. pii: S0960-9822(14)01041-0. doi: 10.1016/j.cub.2014.08.028. [Epub ahead of print]
• Klein R, Kania A (2014)
  Ephrin signalling in the developing nervous system Curr Opin Neurobiol
  Curr Opin Neurobiol. 2014 Mar 6;27C:16-24. doi: 10.1016/j.conb.2014.02.006. [Epub ahead of print]
• Klein P, Müller-Rischart AK, Motori E, Schönbauer C, Schnorrer F, Winklhofer KF, Klein R (2014)
  Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants
  EMBO J. 2014 Jan 28. [Epub ahead of print]
• Leyva-Díaz E, Del Toro D, Menal MJ, Cambray S, Susín R, Tessier-Lavigne M, Klein R, Egea J, López-Bendito G (2014)
  FLRT3 Is a Robo1-Interacting Protein that Determines Netrin-1 Attraction in Developing Axons
  Curr Biol. 2014 Feb 18. pii: S0960-9822(14)00075-X. doi: 10.1016/j.cub.2014.01.042. [Epub ahead of print]
• Mishra A, Traut MH, Becker L, Klopstock T, Stein V, Klein R (2014)
  Genetic Evidence for the Adhesion Protein IgSF9/Dasm1 to Regulate Inhibitory Synapse Development Independent of its Intracellular Domain
  J Neurosci. 2014 Mar 19;34(12):4187-99. doi: 10.1523/JNEUROSCI.3671-13.2014.
• Schaupp A, Sabet O, Dudanova I, Ponserre M, Bastiaens P, Klein R (2014)
  The composition of EphB2 clusters determines the strength in the cellular repulsion response
  J Cell Biol. 2014 Jan 27. [Epub ahead of print]
• Seiradake E, Del Toro D, Nagel D, Cop F, Härtl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R (2014)
  FLRT Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
  Neuron. 2014 Oct 22;84(2):370-85. doi: 10.1016/j.neuron.2014.10.008. Epub 2014 Oct 22.
• Serradj N, Paixão S, Sobocki T, Feinberg M, Klein R, Kullander K, Martin JH (2014)
  EphA4-Mediated Ipsilateral Corticospinal Tract Misprojections Are Necessary for Bilateral Voluntary Movements But Not Bilateral Stereotypic Locomotion
  J Neurosci. 2014 Apr 9;34(15):5211-21. doi: 10.1523/JNEUROSCI.4848-13.2014

2013

• Paixão S, Balijepalli A, Serradj N, Niu J, Luo W, Martin JH, Klein R (2013)
  EphrinB3/EphA4-Mediated Guidance of Ascending and Descending Spinal Tracts
  Neuron. 2013 Dec 18;80(6):1407-20. doi: 10.1016/j.neuron.2013.10.006.