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Meis1 effects on motor phenotypes and the sensorimotor system in mice

Dis Model Mech. 2017 Jun 23. pii: dmm.030080. doi: 10.1242/dmm.030080. [Epub ahead of print] .

Authors/Editors: Salminen AV, Garrett L, Schormair B, Rozman J, Giesert F, Niedermeier KM, Becker L, Rathkolb B, Rácz I; German Mouse Clinic Consortium, Klingenspor M, Klopstock T, Wolf E, Zimmer A, Gailus-Durner V, Torres M, Fuchs H, de Angelis MH, Wurst W, Hölter SM, Winkelmann J.
Publication Date: 2017

salminen-2017

SUMMARY STATEMENT

Loss of Meis1 results in motor restlessness in mice; a phenotype resembling human restless legs syndrome, as well as altered sensorimotor gating and improved social discrimination memory.

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